China's top respiratory expert, the leader of the high-level expert group of the National Health Commission, Zhong Nanshan said in a webinar with overseas Chinese students, Lianhua Qingwen capsule has been proven effective for the treatment of virus. Effect of aqueous extract of Lianhuaqingwen Capsule on bacterial biofilm of methicillin-resistant Staphylococcus aureus [J]. Get new journal Tables of Contents sent right to your email inbox, http://creativecommons.org/licenses/by/4.0, Http://www.nhc.gov.cn/jkj/s7916/202001/44a3b8245e8049d2837a4f27529cd386.sht-ml, https://www.who.int/dg/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-, http://www.nhc.gov.cn/yzygj/s7653p/202002/8334a8326dd. TheDangerous Drug Board (DDB)considers ephedrine as a dangerous drug, andthose found to be sources are also classified as dangerous drugs. Do not use this product if the property changed. Add your comment to start the conversation. Medicine. All patients must be diagnosed with prediabetes by clearly defined or internationally recognized criteria. Fish catch in Guimaras decreased by 29.6 percent from 7,844.53 metric tons in 2021 to 5,517 metric tons in 2022, as reported by the Chinese supplement Lianhua Qingwen: What you need to know, LOOK FOR BACKUP POWER: MORE Power assures 100% supply after weekend, Marcos prods NGCP to address energy woes in Western Visayas, Remains of two persons found dumped in concrete pipe, Guimaras fish yield down by 29.67% in 2022, DOE: Power reserves may run low in May, June, Globe secures ~P40.5B from its P91-B tower sale and leaseback, USTR keeps PH out of watchlist for 10 years, cites best, Iloilo taekwondo team hailed as overall champions in 2023 WVRAA meet, Gilas Pilipinas frontcourt woes continue as Aguilar & Erram ruled out, Kaya FC-Iloilo demolishes Mendiola FC in PFL clash, NBA Playoffs: Currys record-breaking 50-point Game 7 leads Warriors past Kings, Record-high 11,013 Filipino nurses took U.S. licensure exam for the first, Expert advice on identifying and treating allergic asthma, WHO and IAPAC sign a memorandum of understanding focused on ending, WHO launches new initiative to improve pandemic preparedness, 90% of countries report disruptions to essential health services since COVID-19 pandemic, Record-high 11,013 Filipino nurses took U.S. licensure exam for the first time in Q1, WHO and IAPAC sign a memorandum of understanding focused on ending epidemics in cities. The capsule was earlier developed in 2003 to treat the severe acute respiratory syndrome (SARS) and extracts the essence of 13 herbs. Methods: [Drug Interactions]Interaction may appear if administered accompanied with other medicine, consult with doctors or pharmacists for details. Lianhuaqingwen (LH) is one of them, which is used to treat COVID-19 with a solid theoretical foundation in the field of TCM. For the treatment of influenza due to heat-toxic attack lung, syndrome see: fever or serious fever,aversion to cold, muscle soreness, stuffy nose, runny nose, cough, headache, throat dry and sore throat, red tongue, yellow or yellow greasy tongue coating and so on. The manuscript was drafted by XLZ and MJL. It cannot be bought over-the-counter and not recommended for self-medication. There are an increasing number of studies on for COVID-19 published with inconclusive results in recent. 10 Progress in pharmacology and clinical research of Lianhuaqingwen capsule [J]. Data is temporarily unavailable. Dont take this medicine if the description has changed. Clearing away heat toxic materials,open the inhibited lung-energy and clearing away lung heat. 12th-Five Year Plan Special Project of National Major New Drug Development National Health and Family Planning Commission of the people's Republic of China. The following electronic bibliographic databases will be searched to identify relevant studies: CNKI, CBM, VIP and Wanfang databases, PubMed, EMBASE, MEDLINE, Cochrane central, and clinical trial registration centers, such as China Clinical Trial Registration Center (ChiCTR), Netherlands National Trial Registration Center (NTR) and clinical trials.gov. The studies that do not fulfill the inclusion criteria will be excluded and listed with reasons for their exclusion. LHQWG was first used in the treatment of influenza, and studies have found that the drug is superior to oseltamivir in improving the symptoms of influenza A virus infection. Novel coronavirus pneumonia treatment plan issued by the national health and Health Committee, State Administration of traditional Chinese medicine (trial version sixth) [EB/OL]. The following data will then be extracted from the studies selected for inclusion using a data collection form, and recorded onto an Excel file: first author and year, study design, sample, intervention, type of measures, risk of bias assessment, and findings. Stage Food and Drug Administration Approval number:Z20040063. A statistically significant difference was identified between the Lianhua Qingwen group and the conventional drug group (OR=3.02, 95% CI=1.23 to 7.42, P=0.016). Pulmonary Imaging Improvement. Five studies reported improvement in pulmonary imaging. Also indicated for the symptoms of fever, cough, and fatigue caused by the mild and moderate coronavirus disease 2019 (COVID-19) in combination with standard of care. Delivery takes 2 business days & another 2 calendar days for order processingPROMO OFFER ( completed & over) : Buy 1 Bundle, We Donate 1 Bundle ! The two groups were compared in terms of clinical effects and main symptom (fever, cough and fatigue) disappearance rate. It has become a representative Chinese patent medicine for public health emergencies of the respiratory system. Sign in to listen to groundbreaking journalism. Avoid receiving nourishing Chinese medicine during the period in this product. The secondary outcomes of this review will include antipyretic time, disappearance rate of fever symptoms, disappearance rate of cough symptoms, disappearance rate of asthenia symptoms, and adverse drug events. CT images of patient Mr. Lin (Male, Fifty-five years old) during different treatment periods. [26]. Children should take under the supervision of adult. Use left/right arrows to navigate the slideshow or swipe left/right if using a mobile device. Chinese Journal of experimental pharmacology 2015;21:13943. A: Before treatment; B: After treatment. Chest radiographs. In 2013, Expert Consensus on Medical Treatment for Patients Infected with H7N9 Avian Influenza (2013), issued by the National Health and Family Planning Commission According to the Cochrane Handbook bias risk assessment tool, bias risk is independently assessed. The findings of the trial showed strong indications of LHQW in helping patients recover faster and in the prevention of severe covid disease, when compared to the control group using only standard treatment. Common side effects are heart palpitations, nausea, and vomiting. The Chinese medicine compound Lianhua Qingwen has been listed as the recommended drug for the diagnosis and treatment of respiratory infectious diseases by the national Wei Jian administration and the State Administration of traditional Chinese medicine for 20 times. Individuals w/ cold deficiencies in spleen & stomach or w/ qi. A: Chest radiograph of normal people; B: Chest radiograph of a patient with early-mid-stage COVID-19. Recently, the novel coronavirus pneumonia (COVID-19) epidemic has spread continuously and has been classified as class B infectious diseases (class a management). BMJ 2008;336:9246. Sofia Tomacruz covers defense and foreign affairs. Lianhua Qingwen formula is based on the theory of collateral disease, to reveal the law of transmission of respiratory infectious diseases caused by virus. COVID-19; Lianhua Qingwen; meta-analysis; protocol; systematic review. [Packaging] Aluminum plastic plate packaging, 24 capsules / box, 400 boxes / case, Listed in National Essential Drug List [14]. cDepartment of lung diseases, the Third Clinical Hospital of Changchun University of Chinese Medicine, Changchun, Jilin, China. If meta-analysis is not applicable, we will conduct a systematic narrative synthesis providing information to summarize and explain the characteristics and findings of the included studies. The Bile Acid Membrane Receptor TGR5 in Cancer: Friend or Foe. WebLianhua Qingwen Dosage & Drug Information | MIMS Thailand Lianhua Qingwen(Forsythiae fructus 225 mg, Lonicerae japonicae flos 225 mg, Ephedrae herba Tips: Please read the directions for use in retail or directed by physician. Kunming: Kunming University of technology; 2015. System searches CNKI, CBM, VIP and Wanfang databases, PubMed, EMBASE, MEDLINE, Cochrane central, and clinical trial registration centers, such as ChiCTR, NTR and clinical Trials.gov. [30] The I2 statistic of <50% indicates a low level of statistical heterogeneity, and that of 50% will be considered substantial statistical heterogeneity. [34]. Efficacy and safety of Lianhua Qingwen combined with conventional antiviral Western Medicine in the treatment of coronavirus disease (covid-19) in 2019: Protocol for a systematic review and meta-analysis. The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology[32] will be used to assess the quality of the evidence and risk of bias with on-line GRADE (https://www.gradeworkinggroup.org/). It is not necessary for ethical approval because this article is based on previously conducted studies and does not involve any new studies of human or animal subjects performed by any of the authors. A: CT at admission (February 14, 2020); B: CT Reexamination after treatment (February 25, 2020); C: CT Reexamination after treatment (March 13, 2020); D: CT Reexamination after discharge (June 11, 2020). Effectiveness and Safety of Lianhua Qingwen Capsules for COVID-19: A Propensity-Score Matched Cohort Study. This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The results will be cross-checked by the 2 reviewers, and any disagreements will be resolved by consensus, with any ongoing differences in opinion being arbitrated by a third reviewer (LMJ). Medicine (Baltimore). 11. National Library of Medicine 2.Its not appropriate to take nourishing chinese medicine wihte taking medicine. Web[Administration and Dosage] For oral administration, 4 capsules once, 3 times a day. V03AX - Other therapeutic products ; Other products with therapeutic properties. The patients receiving Lianhua Qingwen Capsule treatment were assigned to the observation group (n=33) and those given conventional therapy were included in the control group (n=33). ACTSmarket.com is the e-shop and distribution arm of ACTSmarket Ltd, The conclusion of this review will provide evidence to judge whether Lianhua Qingwen combined with Conventional antiviral Western Medicine is an effective and safe intervention for COVID-19. She can be reached atbandiolateresamayb@gmail.com. Hongying Mo, Zifeng Yang, Jinping Zheng, et al. All randomized controlled trials (RCTs), Retrospective cohort study (RCSs), Comparison before and after the study (BAs) of Lianhua Qingwen combined with Conventional antiviral Western Medicine for COVID-19 will be included. Used in treatment of epidemic influenza and lung heat, symptom as fever or high fever, aversion to cold, muscular soreness, rhinostegnosis and nasal discharge, cough, headache, dry and sore throat, flushing tongue, or greasy fur of tongue. 4 capsules per dose. It is approved by HSA asan over-the-counter traditional Chinese medicine to treat influenza and colds. The assessment will be adjudicated into 4 levels: high, moderate, low, or very low. Lianhuaqingwen (LHQW) has anti-inflammatory and immune regulatory functions and may inhibit the airway inflammation that occurs during an acute exacerbation of COPD. Middle East respiratory syndrome case diagnosis and treatment program (2015 Edition) [J]. Traditional Chinese medicine, such as Lianhua Qingwen, has achieved some curative effect in many countries, but its effect is not clear. Articles in Google Scholar by Xiaolin Zhang, MD, Other articles in this journal by Xiaolin Zhang, MD, Intermediate dose cytarabine improves survival and relapse-free rate compared with standard-dose cytarabine as post-remission treatment for acute myeloid leukemia: A retrospection study, Privacy Policy (Updated December 15, 2022). SHIJIAZHUANG YILING PHARMACEUTICAL CO., LTD. Lianhua Qingwen, a representative TCM patent product for the treatment of influenza. For the treatment of COVID-19, the main effects of Lianhua Qingwen are as follows: First, after taking the capsule, patients' symptoms improve quickly, two days earlier than the control group. Second, CT scan result also shows that patients recover faster than the control group. Third, the capsule can shorten fever time. After determining how to combine different types of studies, NRIs use the method of inverse variance of random-effect model to evaluate and calculate the 95% CI of the effect value. Part of the goods frequent replacement of packaging, such as goods and pictures are not exactly the same, please refer to the goods you receive. National Class- A Varieties for Medical Insurance Drugs Holshue ML, DeBolt C, Lindquist S, et al. While it has been included in the standard treatment for coronavirus patients in China, it faces hurdles in the West where scientists raise questions over the evidence and effectiveness of traditional medicine. Zhang, Xiaolin MDa,; Cao, Di MMb; Liu, Junnan MMa,c; Zhang, Qi MDa; Liu, Mingjun PhDa,, aChangchun University of Chinese Medicine. It is compatible with Rhodiola to clear lung and remove blood stasis. Clipboard, Search History, and several other advanced features are temporarily unavailable. Please be informed that only the Should not be used for wind-cold common cold. Consultancy by Fixx Digital Lianhua Qingwen combined with conventional antiviral Western Medicine may be a useful treatment for prediabetes. It has a history of abuse by athletes due to its ability to increase energy and alertness and help weight loss. < 5 years: not recommended because it may be difficult for young children to swallow capsules. [19]. doi: 10.1097/MD.0000000000021404. The Philippines Food and Drug Administration (FDA) has approved the traditional Chinese medicine (TCM) capsule Lianhua Qingwen widely used in China as Buy Hongying Mo, Changwen Ke, Jinping Zheng, et al. Please protect from moisture after opening the moisture proof bag. If 2 eligible RCTs are identified, meta-analysis will be performed with Review Manager 5.3. Learn more. The 3 drugs and 3 parties in China have been effective in many countries around the world, and once again reveal the special advantages of the Chinese herbal medicine overall adjustment and multi target therapy, which suggests the application of Lianhua Qingwen granule. Before For more information, please refer to our Privacy Policy. Is there any notice for taking Lianhua Qingwen Capsules? 2023 Feb 17;2023:6028554. doi: 10.1155/2023/6028554. In 2014, Diagnosis and Treatment Scheme for Patients Infected with H7N9 Avian Influenza (2014), issued by the National Health and Family Planning Commission Ding Y, Zeng L, Li R, et al. Study on the effect of Lianhuaqingwen Granule on BALB /c mice infected with respiratory syncytial virus [J]. Now. The PRISMA-P (Preferred Reporting Items for Systematic review and Meta-Analysis Protocols) checklist of this protocol is presented in PRISMA-P checklist. To clear scourge and remove toxin, diffuse the lung and discharge heat. Domingo said this version of the capsule was still unregistered to date, meaning the FDA could not guarantee its quality and safety. Lianhua Qingwen, which was approved by China Food and Drug Administration (CFDA) in 2004, was the first traditional Chinese medicine that entered the rapid drug approval channel of the CFDA and was used to prevent severe acute respiratory syndrome (SARS). Writing original draft: Xiaolin Zhang, Di Cao. Preliminary Study on the Inhibitory Effect of Lianhuaqingwen Capsule on Virus [D]. Copyright 2023 MIMS Pte Ltd. All rights reserved. [Functions and Indications]Clear heat and detoxify, remove lung hotness. LHQW won the 2nd prize of the National Scientific and Technological Progress Award in 2011 for the treatment of influenza. (For Children 4 to 18 years of age): 3 times daily. Infants / children aged below 4 years are not recommended to consume. [8]. A park employee (R), seen wearing goggles and face mask, walks in a park in Beijing on March 14, 2020. Please try again soon. If use with the other drugs at the same time may occur drug interactions,details please consult your physician or pharmacist. Post code: 050035 Tel: 0086-311-85901643 Fax: 0086-311-85906730 Website: http://www.yiling.cn Any questions or problems, please do not hesitate to contact manufacturer. The treatment strategy of active intervention is put forward, which includes the treatment of both exterior and interior, the treatment of syndrome first, the treatment of disease cutting off, the overall adjustment, and multitarget treatment. 8600 Rockville Pike However, there are individual differences in the efficacy of traditional Chinese medicine compound Lianhua Qingwen, which makes the quality of evidence of clinical efficacy of traditional Chinese medicine low. Hongtao Lei, Shutu Ma, Xiuxin Jiang, et al. Follow her on Twitter via @sofiatomacruz. Two reviewers (XLZ and JNL) will assess the eligibility of the studies retrieved during the searches independently using the inclusion and exclusion criteria. The full text of articles potentially suitable for the review will be obtained for further assessing eligibility based on the inclusion criteria or/and exclusion criteria. Chest radiographs of the patient. Used for patterns of heat toxin assailing the lung in flu, manifested as fever, aversion to cold, muscle soreness, stuffy & runny nose, cough, headache, dry & sore throat, reddish tongue, yellow & greasy tongue coating. Heart or thyroid disease, high BP, diabetes, glaucoma, HTN, tumor of adrenal gland, difficulty in urination due to the enlargement of the prostate gland. - China reported 11 new infections of the coronavirus on March 14, and for the first time since the start of the epidemic the majority of them were imported cases from overseas. BMC Complement Altern Med 2017;17:130. Placebo, routine western medicine therapy, and other therapeutic methods in the comparators (drugs, dose, frequency, duration); (5) Outcomes: the primary outcomes include total efficiency, primary symptoms, and Also illustrates the potential biases within each of the included studies by presenting a risk of bias," table, graph, and summary. Avoid cigarettes, alcohol and keep from eating spicy, raw, cold or greasy food. 1. If I2 test <50%, a fixed-effects model will be used to pool the data. Copyright Shijiazhuang Yiling Pharmaceutical Co,Ltd. Dosage: 2 capsules twice a day ( after breakfast & dinner). [Storage]Preserve in tightly closed containers, stored in a cool and dry place (20). [Package]Aluminium-plastic package, 24 capsules/box, [Executive Standard]Chinese Pharmacopoeia 2010, the 2nd supplemental volume. Its formulation includes 13 herbs which are said to have been used for medical purposes as early as the Han dynasty. 5.Children, preganant or lactation women,elderly ,feeble and weak patients ,spleen and stomach weakness patients should be taken under the guidance of physician. 7. Bioinform Biol Insights. Chunyuan Liu, Xiaoqiang Li, Shaoqian Cai. The independent Newcastle Ottawa scale was used to conduct methodological quality assessment of nonrandomized trials. If substantial heterogeneity is identified, we will report it and explore possible causes using sensitivity analysis and subgroup analysis. Avoid spicy & greasy food during medication. 2 capsules per dose. Keyword Highlighting Ephedra increases heartbeat and blood pressure. There are no comments yet. Evid Based Complement Alternat Med. National Key New Product [Functions and Indications] Lianhua Qingwen (LHQW), a Chinese supplement approved by the Philippine Food and Drug Administration (FDA) for mild Covid-19 symptoms, continues to We plan to carry out the following subgroup analyses if possible: the study area is different, the average course of disease is different, and the length of treatment is different. Ephedrine isanamphetamine-like compound, which is an addictive stimulant of the central nervous system. WebLianhua Qingwen Jiaonang with Chinese Characters; As per continuing post-marketing surveillance, there is still incessant sale and distribution even through social media platforms, such as Facebook, of Lianhua Qingwen Jiaonang with Chinese characters, which were verified as unregistered by the FDA. Max: 7 days. You may search for similar articles that contain these same keywords or you may The study was financially supported by the National Natural Science Foundation of China (Grant Number 86174092) and a grant from the School construction project of State Administration of traditional Chinese medicine (Grant Number LPGZS22014-11). As stated in the research paper published on "Scientific World Journal", Lianhua-Qingwen capsule (LQC) is a commonly used Chinese medical preparation to treat virus and especially played a very important role in the fight against severe acute respiratory syndrome (S-A-R-S) in 2002-2003 in China. Avoid prolonged use. 3.Patients with common cold due to wind-cold dont apply to the product. The Chinese medicine compound Lianhua Qingwen has been listed as the recommended drug for the diagnosis and treatment of respiratory infectious diseases by It has important clinical significance for alleviating the severity of COVID-19 and shortening the course of disease. [1]. JAMA Intern Med 2020;March 13 (Epub ahead of print). How to Use: Dosage: Consume orally 4 capsules each, 3 times daily after meal. In 2018, Diagnosis and Treatment Scheme for Influenza (2018), issued by the National Health and Family Planning Commission The patients receiving Lianhua Qingwen Capsule treatment were assigned to the observation group (n=33) and those given conventional therapy were included in Remdesivir in adults with severe, [13]. For oral use after meals,4 capsules thrice daily or by medical ordor5 boxes for a treatment Risk ratio (RR) was used to express the severe conversion rate and CT improvement rate absorption rate; mean difference (MD) was used to express the time of fever reduction in secondary indexes; Odds Ratio (OR) was used to express clinical efficiency and symptom disappearance rate. a non-profit social enterprise that collaborates with other SE producers to build capacity in marketing, sales and operations. All tests are 2-tailed, and P < .05 is considered statistically significant. Federal government websites often end in .gov or .mil. The 700 boxes of LHQW are sponsored by Yiling Pharmaceutical Co. Ltd (China) and the local distributorKinhong Pte Ltd. It is based on the published clinical research literature at present stage. J Integr Med. Pregnancy & lactation. Biotechnology communication 2003;14:3902. Subgroup analysis and sensitivity analysis will be performed to explore the causes of heterogeneity. Already have Rappler+? 10. In PubMed, MEDLINE, and EMBASE, search with Lianhua Qingwen and COVID-19 as subject words. This site needs JavaScript to work properly. The capsule was earlier developed in 2003 to treat the severe acute respiratory syndrome (SARS) and extracts the essence of 13 herbs. Copyright 2023 MIMS Pte Ltd. All rights reserved. [Adverse Reactions]Post-marketing monitoring data show that this product may cause gastrointestinal adverse reactions such as nausea, vomiting, abdominal pain, diarrhea, bloating, as well as rash, itchy ulcers, dry mouth, dizziness. Aside from the Philippines, the Lianhua Qingwen Capsule has been approved in Hong Kong and Macau, Brazil, Indonesia, Canada, Mozambique, Romania, Thailand, Ecuador, Singapore and Lao. [Contraindications]Those who are allergic to this product and its ingredients should not take it. Meta-analysis on the effect of combining Lianhua Qingwen with Western medicine to treat coronavirus disease 2019. Molecules. To systematically determine the effect of Lianhua Qingwen Capsules on the early antiviral and anti-inflammatory action against COVID-19 (Coronavirus 2019) and its applicational value in the treatment of COVID-19. Here are links to the publications that published the results of the clinical trial :https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229744/https://en.prnasia.com/releases/global/tcm-lianhua-qingwen-shows-stable-in-vitro-antiviral-effect-on-the-delta-variant-expert-327965.shtmlIngredients & ContradicationsPlease refer to the pictures for more informationUSAGE FOR RESPIRATORY DISEASES SUCH AS FLUS AND COLDSProphylaxis: If you know you are going out, take LHQW the day before, the day of the outing and the day after the outing. Before the successful development of targeted vaccine, >4 million patients with covid-19 and asymptomatic infection around the world may also benefit from traditional Chinese medicine such as Lianhua Qingwen. Third, the capsule can shorten fever & coughting time. BMJ 2003;327:55760. https://en.prnasia.com/releases/global/tcm-lianhua-qingwen-shows-stable-in-vitro-antiviral-effect-on-the-delta-variant-expert-327965.shtml, Lianhua Qingwen Jiangnan (LHQW) for Flu and Colds. Bias in. eCollection 2020. Here, we chose a thirteen-component TCM formula, Lianhua Qingwen capsule (LHQW), as a Writing review & editing: Xiaolin Zhang. 2022 Aug;47(16):4505-4516. doi: 10.19540/j.cnki.cjcmm.20220510.501. The rate of positive nucleic acid detection of COVID-19 from intranasal and pharyngeal swabs was significantly lower in the treatment group In addition, it can also interact with other compounds and herbs. Following the outbreak of Covid-19 in Wuhan, a randomized clinical study, led by top TCM physicians, was conducted to study its efficacy in treating Covid-19. [Administration and Dosage] In this study, 100 participants were Wolters Kluwer Health Race to find. > 5 to <12 years old: 2 to 3 capsules x 3 times a day ( after breakfast, lunch and dinner). How to take it to realize the maximal efficacy? LHQW is approved by China'sNational TCM Administration for the treatment of mild covid-19. >10 to <14 years old: 3capsules x 3 times a day ( after breakfast, lunch and dinner).> 5 to <12 years old: 2 to 3 capsules x 3 times a day ( after breakfast, lunch and dinner). Press the space key then arrow keys to make a selection. FREE SHIPPING within SG when you buy 4 boxes or more. We may also contact the original authors to provide additional relevant information, if necessary. Careers. [23]. Teresa May Bandiola is a licensed pharmacist, a published writer, and a university instructor. This product should be administered strictly in accordance with dosage and administration, and is not for long-term use. Whether a fixed-effects or a random-effects model will be used depends on the results of I2 test for heterogeneity. 4.Patients with diabetes patients,high blood pressure, heart diseases, liver disease, kidney disease and other severe chronic diseases shall take medicine under guidance of physician. Also excluded are studies enrolling <30 participants. STATA15.1 and RevMan5.3 software were used to analyze meta outcomes of different intervention measures for the treatment of new crown pneumonia and the control group (conventional antiviral western medicine treatment) clinical efficacy. Not suitable for long-term use. Unauthorized use of these marks is strictly prohibited. The data extraction form will include the following items: Two reviewers/authors (ZXL and ZQ) will independently evaluate the quality of the included trials through assessing the risk of bias using the following tools, when appropriate: The following aspects of included trials will be assessed: sequence generation, allocation concealment, blinding of participants, personnel and outcome assessors, incomplete outcome data, and selective outcome reporting. Correct way is to take it orally, 3 capsules 1 time, 3 times a day. Product PackingEach box contains 24 capsules in blister packing. Available at: [30]. The protocol will be disseminated in a peer-reviewed journal or presented at a relevant conference. The DDB, however, had no objections to the product registration ofLHQWwith the Philippine FDA and said that the importer or distributor shall secure the proper license from thePhilippine Drug Enforcement Agency (PDEA) and comply with all regulatory requirements and relevant issuances. China's top respiratory expert,the leader of the high-level expert group of the National Health Commission, Zhong Nanshan said in a webinar with overseas Chinese students, Lianhua Qingwen capsule has been proven effective for the treatment of virus. The course of treatment is 7-10 days for patients with mild and moderate COVID-19. 13. We aim to assess the efficacy and safety of Lianhua Qingwen combined with Conventional antiviral Western Medicine in Clinical treatment of COVID-19 or asymptomatic infection. HHS Vulnerability Disclosure, Help
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